Detalhe da pesquisa
1.
The Translation Inhibitor Rocaglamide Targets a Bimolecular Cavity between eIF4A and Polypurine RNA.
Mol Cell
; 73(4): 738-748.e9, 2019 02 21.
Artigo
Inglês
| MEDLINE | ID: mdl-30595437
2.
Structural basis of transcription regulation by CNC family transcription factor, Nrf2.
Nucleic Acids Res
; 50(21): 12543-12557, 2022 11 28.
Artigo
Inglês
| MEDLINE | ID: mdl-36454022
3.
N-(3,4-dimethoxyphenethyl)-6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-amine inhibits bladder cancer progression by suppressing YAP1/TAZ.
Genes Cells
; 27(10): 602-612, 2022 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-36054428
4.
Establishment of a Monoclonal Antibody against Human NTCP That Blocks Hepatitis B Virus Infection.
J Virol
; 96(5): e0168621, 2022 03 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34985994
5.
Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti.
BMC Biol
; 20(1): 43, 2022 02 17.
Artigo
Inglês
| MEDLINE | ID: mdl-35172816
6.
Pharmacological intervention of cholesterol sulfate-mediated T cell exclusion promotes antitumor immunity.
Biochem Biophys Res Commun
; 609: 183-188, 2022 06 18.
Artigo
Inglês
| MEDLINE | ID: mdl-35452959
7.
Protein-ligand binding affinity prediction of cyclin-dependent kinase-2 inhibitors by dynamically averaged fragment molecular orbital-based interaction energy.
J Comput Chem
; 43(20): 1362-1371, 2022 07 30.
Artigo
Inglês
| MEDLINE | ID: mdl-35678372
8.
Selective Inhibitor Design for Kinase Homologs Using Multiobjective Monte Carlo Tree Search.
J Chem Inf Model
; 62(22): 5351-5360, 2022 11 28.
Artigo
Inglês
| MEDLINE | ID: mdl-36334094
9.
New antimalarials identified by a cell-based phenotypic approach: Structure-activity relationships of 2,3,4,9-tetrahydro-1H-ß-carboline derivatives possessing a 2-((coumarin-5-yl)oxy)alkanoyl moiety.
Bioorg Med Chem
; 66: 116830, 2022 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35594648
10.
Alantolactone is a natural product that potently inhibits YAP1/TAZ through promotion of reactive oxygen species accumulation.
Cancer Sci
; 112(10): 4303-4316, 2021 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-34289205
11.
Novel bicyclic pyrazoles as potent ALK2 (R206H) inhibitors for the treatment of fibrodysplasia ossificans progressiva.
Bioorg Med Chem Lett
; 38: 127858, 2021 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33609658
12.
Special Features of COVID-19 in the FMODB: Fragment Molecular Orbital Calculations and Interaction Energy Analysis of SARS-CoV-2-Related Proteins.
J Chem Inf Model
; 61(9): 4594-4612, 2021 09 27.
Artigo
Inglês
| MEDLINE | ID: mdl-34506132
13.
FMODB: The World's First Database of Quantum Mechanical Calculations for Biomacromolecules Based on the Fragment Molecular Orbital Method.
J Chem Inf Model
; 61(2): 777-794, 2021 02 22.
Artigo
Inglês
| MEDLINE | ID: mdl-33511845
14.
Structural basis of protein arginine rhamnosylation by glycosyltransferase EarP.
Nat Chem Biol
; 14(4): 368-374, 2018 04.
Artigo
Inglês
| MEDLINE | ID: mdl-29440735
15.
Discovery of trypanocidal coumarins with dual inhibition of both the glycerol kinase and alternative oxidase of Trypanosoma brucei brucei.
FASEB J
; 33(11): 13002-13013, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31525300
16.
High-Precision Atomic Charge Prediction for Protein Systems Using Fragment Molecular Orbital Calculation and Machine Learning.
J Chem Inf Model
; 60(7): 3361-3368, 2020 07 27.
Artigo
Inglês
| MEDLINE | ID: mdl-32496771
17.
Interruption of Vif/Elongin C interaction: In silico and experimental elucidation of the underlying molecular mechanism of benzimidazole-based APOBEC3G stabilizers.
Bioorg Med Chem
; 28(8): 115409, 2020 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32169404
18.
Force-field parametrization based on radial and energy distribution functions.
J Comput Chem
; 40(29): 2577-2585, 2019 11 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31343749
19.
New SIRT2 inhibitors: Histidine-based bleomycin spin-off.
Bioorg Med Chem
; 27(9): 1767-1775, 2019 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30885568
20.
A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity.
Nature
; 503(7477): 493-9, 2013 Nov 28.
Artigo
Inglês
| MEDLINE | ID: mdl-24172895